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Mental stress should be addressed among individuals with obesity, as chronic stress may promote obesity development through the sympathetic nervous system and hypothalamic-pituitary-adrenal axis activation that elevates cortisol levels, interferes with insulin sensitivity, promotes energy storage, and creates food cravings for ultra-processed comfort foods [180] GLP-1s may act both centrally and peripherally to reduce these downstream impacts of chronic stress and obesity and alter food reward pathways in positive ways [124]

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Those averaging under 50 ounces accounted for three hospitalizations for dehydration and two for acute kidney issues

The same appetite suppression that drives weight loss also makes it difficult to eat enough protein

Training without adequate protein limits the bodys ability to repair and maintain tissue

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