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Combined therapy with two classes of antidiabetic agents, namely, dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter-2 inhibitors, target several pathophysiological pathways

[4] However, according to Harvard Health [5], there are potentially more serious side effects including pancreatitis, gastroparesis, bowel obstruction and gallstones

The standard dose is 2 mg once weekly, administered on the same day each week regardless of meals

doi: 10.1001/jama.2024.6586

[22] Metoclopramide (Reglan) works by promoting gastric emptying, theoretically counteracting the GLP-1 mechanism, but carries a boxed warning for tardive dyskinesia and should not be used for longer than 12 weeks except in rare circumstances

doi:10.1038/s41392-024-01951-9 Uusitupa M, Khan TA, Viguiliouk E, et al