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DHA significantly upregulates the mRNA expressions of BNIP3, NIX1, and NIX2 and promotes mitophagy in the abdominal adipose tissue of grass carp ( Ctenopharyngodon idellus ), in turn enhancing the mRNA expressions of caspase9, caspase3a, caspase3b, and Bax, and Bax/Bcl-2 ratio, and down-regulating that of Bcl-2
The combined effects could produce excessive sedation or respiratory depression
Cysteine is often the "limiting factor" in this process
In comparison to the control, growth of MRAB isolates in presence of amikacin were significantly reduced from 6 g/ml amikacin for MRAB-1 and -2, and from 8 and 10 g/ml amikacin for MRAB-3 and -4, respectively (B)
Bone morphogenetic proteins (BMPs) are the most representative example, which have been granted US Food and Drug Administration (FDA) approval for clinical applications in recalcitrant long bone non-unions, lumbar fusion and open tibial shaft fractures [1618]