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Vanuytsel, T

Youre more likely to experience small tears that can damage the esophagus and potentially lead to bleeding

[33] Based on the clinical dosing regimen (2.5 to 5 mg TZP weekly), we estimated that a depot designed to release TZP continuously over four months in a rat model should contain approximately 4.5 mg of drug within a subcutaneously injectable volume (typically 0.5 to 2 mL)

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Aim for 0.5-1% of body weight lost per weekthat's 1-2 pounds weekly for a 200 lb person