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The narrative of cost-neutral by reducing diabetes/hypertension costs was not supported short-term

GSH in fact is both a nucleophile and a reductant, and therefore can react with electrophilic or oxidizing species rendering the former molecules more soluble and excretable, and the latter unable to interact with more critical cellular constituents such as lipids, nucleic acids and proteins

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These analyses compared GLP-1 receptor agonists with other glucose-lowering medications such as DPP-4 inhibitors and insulin