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It is mainly characterized by fatigue that is not significantly relieved by rest, often accompanied by heterogeneous symptoms such as generalized body, muscle, and joint aches, mood disturbances, and sleep difficulties

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It also lowers the risk of heart-related complications in people with diabetes

Science 355 , 722 (2017)

Metformin administration during early postnatal life rescues autistic-like behaviors in the BTBR T+ Itpr3tf/J mouse model of autism

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