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In summary, the HPA axis is a key component of the MGBA, and a possible mechanism is that VNS modulates PD-related neuropsychiatric symptoms by regulating HPA axis function via the vagus nerve

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10.1016/j.berh.2014.01.009 14 BensaA.SalernoM.MoracaG.BoffaA.McIlwraithC