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The Pro-Tumour Role of Nrf2 While many studies indicate that Nrf2 prevents cell stress in normal cells and inhibits tumourigenesis, a substantial amount of data support a pro-tumour role of Nrf2 since many types of tumours display Nrf2 high levels or overstimulation of Nrf2-mediated signalling

The Tg gene is a crucial thyroid-specific antigen located on chromosome 8q24 and also in the bloodstream, which makes it a prime target for autoimmune reactions

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