does vitamin b12 injections cause weight gain and Loss: How it Work? B12 Injections & Weight Loss:

Research suggests that adequate B12 levels support the regeneration of damaged nerve fibres by promoting the synthesis of nucleic acids necessary for cell division and repair

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The absorption process is significantly hindered in conditions such as pernicious anemia, Crohns disease, celiac disease, and following ileal surgical resection, all of which can impair B12 absorption and contribute to suboptimal supplementation outcomes

Otherwise, b12 addition affects weight outcomes minimally or not at all