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Results are variable and depend on device, settings, and anatomy
Gastrointestinal adverse effects are among the most commonly reported challenges with GLP-1 medications, with frequency varying by product, dose and indication
Homge M, Pereira J, Kernan NA, Black P, O'Reilly RJ, Pinkel D, Gray J, Andreeff M
Abbreviations ACC: Acetyl-CoA carboxylase AMPK: AMP-activated protein kinase ATGL: Adipose triacylglycerol lipase BAT: Brown adipose tissue CPT1: Carnitine palmitoyltransferase 1 FBG: Fasting blood glucose GLP-1: Glucagon-like peptide-1 GLP-1R: GLP-1 receptor H&E: Haematoxylin and eosin HFD: High-fat diet HSL: Hormone-sensitive lipase IHC: Immunohistochemical ITT: Insulin tolerance test MEF: Mouse embryonic fibroblast PGC-1: Peroxisome proliferator-activated receptor coactivator-1 mtDNA: Mitochondrial DNA PPAR: Peroxisome proliferation activated receptor RNAi: RNA interference sh: Short hairpin SIRT1: Sirtuin 1 TG: Triacylglycerol UCP-1: Uncoupling protein-1 WAT: White adipose tissue References Twig G, Afek A, Derazne E et al (2014) Diabetes risk among overweight and obese metabolically healthy young adults
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An update on immune-based alpha-synuclein trials in Parkinsons disease
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