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To test this hypothesis, liraglutide, an agonist of GLP-1/GLP-1R, was used to upregulate GLP-1R signals in our OA rat model

Stroma-activated integrin-linked kinase (ILK) supports survival of leukemic cells via stimulation of Notch-Hes signaling: new therapeutic opportunities

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While both settings report meaningful weight loss, real-world studies in 2025 indicate slightly lower outcomes