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Some patients are trained to self-inject after the first few doses at the clinic

At minimum, check metabolic panels, liver function, lipid profiles, and fasting glucose before starting and every 8-12 weeks during combination therapy

Then, 1000 mcg weekly for a month, and 1000 mcg monthly after that

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(2009) Effectiveness of vitamin B12 in treating recurrent aphthous stomatitis: a randomized, double-blind, placebo-controlled trial

If you're feeling particularly rough, you might benefit from additional "boosters" like anti-nausea medication (usually Zofran), anti-inflammatory pain relievers (like Toradol), NAD+ for cellular energy, amino acids for recovery, or additional electrolytes like potassium and calcium