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2) Artery Hardening High levels of TMAO were associated with increased cIMT (carotid intima-media thickness), an early marker for hardening of the arteries (atherosclerosis), in 220 people irrespective of other factors, such as insulin resistance, obesity, and fatty liver [13]

Plasma preparation We separated the resulting plasma into four preparation conditions that differed in anticoagulant used during sample collection, storage temperature, and time to deproteinization

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A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis