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Although the exact pathways involved are still unclear, future research between the GLP-1R agonists and GLUT1 or other molecules in BECs may provide more therapeutic targets for early interventions of BBB breakdown in neurodegenerative diseases especially AD (Figure 1)

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Recent studies have suggested that depression is accompanied by memory loss as well as depressive mood

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Radiology 272 , 568576 (2014)