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Importantly, Dihexa simultaneously increases expression of anti-inflammatory interleukin-10 (IL-10), suggesting the peptide actively shifts the neuroinflammatory balance toward resolution rather than simply suppressing inflammation

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Structure and function of NAD kinase and NADP phosphatase: key enzymes that regulate the intracellular balance of NAD(H) and NADP(H)

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These distinctionsparticularly in gene regulation and cellular signalingoffer important insights for experimental models exploring repair and regeneration