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Future research should integrate longitudinal population studies, mechanistic experiments, and circadian rhythm assessments to determine whether prolactin should be considered a driver, regulator, or biomarker of obesity-related metabolic disorders, thereby providing a theoretical basis for more refined and individualized clinical strategies

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In severe osteoarthritis, the limiting problem is often structural joint degeneration

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5 More importantly, if the early and/or the most treatable stage is missed, liver transplantation is the only option to improve the survival of patients with acetaminophen-induced hepatotoxicity (AIH)