Given the high rate of gastrointestinal tolerability challenges and resultant discontinuation that is characteristic of GLP-1 therapy, we believe that a personalized approach to GLP-1 titration and dosing, including a mealtime bolus option, would give patients an opportunity to reach their treatment goals, while experiencing easier therapy initiation and a more tolerable maintenance regimen, said Jeb Besser, CEO of Modular Medical.
Pharmacy benefit managers increasingly employ step therapy protocols, requiring trial of less expensive agents before approving GLP-1 receptor agonists
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These cells may promote fibrosis through TGF- secretion but could also facilitate its resolution via IL-10 (138)
