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Another related mechanism is that the drug class could reduce uveitis risk through promotion of weight loss, since obesity is known to increase risk of various autoimmune disorders

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European Journal of Pharmacology, 570(1-3), 212-221

For GSK3 overexpression, cardiomyocytes were transfected with a plasmid encoding constitutively active GSK3 using Lipofectamine 3000 reagent (Invitrogen), following the manufacturers instructions

2: moderate

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