Obesity, currently defined as a body mass index (BMI) of 30 kg/m 2 or greater, affects 800 million people worldwide [1]
FDA-Approved Indications for Zepbound: Adults with obesity (BMI 30 kg/m)
How do oligonucleotide chemical modifications, such as 2-OMe and phosphorothioates, affect innate immune activation
Naqvi N, Ahuja K, Selvapandiyan A, Dey R, Nakhasi H, Puri N (2017) Role of Mast Cells in clearance of Leishmania through extracellular trap formation
10.1038/s41577-019-0240-6 20 DuttaS.MukherjeeA.NongthombaU
e.g., exenatide, liraglutide, and semaglutide) are both used for T2D treatment, but they also lead to bodyweight loss, largely accounted for by body fat reduction