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We hypothesize that reduced CPT-I activity may contribute to persistent fatigue in these congenital hypothyroid patients, even after levothyroxine therapy, which alone may be insufficient to fully address the downstream metabolic consequences of TPO and TSHR gene mutations present in this cohort

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136,137,138 Research and clinical trials have shown that tirzepatide not only improves blood sugar levels but also has a positive impact on cardiovascular risk factors

The MT-CYB, CYC1, and UQCRFS1 encoded proteins constitute the electron transfer center of complex III

Weight-bearing exercise (walking, jogging or any exercise done on the feet) and strength training for muscles can help fortify bones and build bone mass

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