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De Cobelli F, Rossini A, Esposito A, Canu T, Manzoni G, Del Maschio A, et al

Diacylglycerol and ceramide accumulation Consistent with the above studies, elevated plasma fatty acid concentrations can result in increased intracellular diacylglycerol (DAG) levels, leading to the activation of protein kinase C isoform (PKC-) and PKC- isoforms in skeletal muscles and liver respectively

After 90 minutes of the first infusion, urinary excretion Glutathione and cysteine increases by 300% and 10% respectively

In Phase I , the liver uses enzymes to turn toxins into smaller, often more reactive intermediate molecules

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doi: 10.4103/ijmr.IJMR_1937_17 2 GanieMAChowdhurySMalhotraNSahayRBhattacharyaPKAgrawalSet al