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This is a type of anemia that is often distinguished by the lack of an intrinsic factor

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Moreover, G289A and T337I mutations are located proximal to the ATP-binding pocket of the C-terminal domain, G289A would cause steric conflict with Ser293, and T337I would cause a hydrophobic patch on the protein surface and reduce protein solubility

This baseline allows objective comparison at three, six, and twelve months

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Una de sus funciones principales es su participacin en la curacin de heridas y la remodelacin de tejidos, donde ayuda a respaldar la produccin de protenas estructurales como el colgeno y la elastina