Synergistic compounds working through different mechanisms can make each component more effective
If ceruloplasmin is below 20 mg/dL at baseline, the patient already has impaired copper-binding capacity
Medically reviewed by: Jayden Lee, PharmD, EMBA Jayden Lee, PharmD, EMBA, is the PlexusDx Medical Science Liaison with a PharmD and MBA specializing in pharmacogenomics and clinical product development, with a proven ability to bridge the gap between genomic research and practical patient outcomes
Generally, however, the matter may come down to a question of scope
The alkaline pH-adapted skin barrier is disrupted severely by SLS-induced irritation
The acid disrupts the copper-peptide bond, releasing free copper while deactivating the GHK tripeptide