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The injection volume was 2 L

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TN, AJS and SEW performed statistical analyses

doi: 10.3389/fneur.2026.1788148 Received 15 January 2026 Revised 16 February 2026 Accepted 23 February 2026 Published 07 April 2026 Volume 17 - 2026 Edited by Paul Chazot, Durham University, United Kingdom Reviewed by Li Baojian, Shaanxi University of Chinese Medicine, China Ayokunmi Akinduko, Landmark University, Nigeria Updates Copyright 2026 Okomolo Moto, Diapa Tchiengang, Kameni Njapdounke, Mbom, Mbeboh Savo, Aren Arsaa, Nezoumne, Ndjock and Bum

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UA and misfolded proteins In addition to core metabolic pathologies such as oxidative stress and inflammation, neurodegenerative diseases are characterized by the deposition of misfolded proteins