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Modulation of the hypothalamic-pituitary-adrenal (HPA) axis by plants and phytonutrients: A systematic review of human trials

Cell Physiol Biochem 40:477485

Introduction The first reports about a plant glutathione S-transferase enzyme (GST, EC 2.5.1.18) appeared in 1970, when it was revealed that a GST catalyzed the detoxification of the herbicide atrazine by its conjugation to the endogenous tripeptide glutathione (GSH, -L-glutamyl-L-cysteinyl-glycine) in sorghum and maize plants (Frear and Swanson, 1970

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10.7150/thno.54113 140 XieL

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