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TB-500 also exhibits clinically relevant anti-inflammatory properties through downregulation of inflammatory cytokines including TNF- and IL-1

901 Osteoclasts are giant, multinucleated cells that arise from the fusion of monocytes/macrophage progenitor cells differentiated from myeloid progenitors in bone marrow

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However, nanocarriers such as polymeric micelles (PEG-PE) that transform antigenic peptides conformation to facilitate cytosolic delivery could be reliably used for LN targeting, APC uptake and antigen cross presentation 75

The PS when correlated with the biochemical findings can be of immense help in identifying the coexisting pathology