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The initial data of this trial were reported at the Alzheimers Association International Conference (2021), revealing no serious adverse events from the intrathecal injection of BIIB080 at either of three doses every month for 3 months or two high-dose injections 3 months apart

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In trials, patients lost an average of 15% of their body weight over 68 weeks

There is no mention of any control over eating or exercise, no mention of weight change, or psychological changes basically no examination of any other factors that could potentially be causing the increased hormonal response separate from ALC

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