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Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia

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If this mechanism can be harnessed for long-lasting modulation, then CRF 1 antagonists, serving as antidepressant, present new potential for application

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The FDA prescribing information includes warnings to monitor for depression and suicidal thoughts, though a direct causal relationship remains unestablished

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