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A treatment session of esketamine consists of instructed nasal self-administration by the patient followed by a period of at least 2 hours post-administration observation of the patient under direct supervision of a health care professional in the certified health care setting

and indeed atypical thalamocortical connectivity in autism has been reported previously(Green et al., 2017

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doi: 10.3390/ijerph15112371 96 GuoQ.LehmerC.Martnez-SnchezA.RudackT.BeckF.HartmannH.et al