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Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor- and bone morphogenetic protein

Weight loss, especially visceral weight loss, induced by the ketogenic diet can reduce estrogen levels by reducing systemic inflammation and hepatic metabolism, potentially also inhibiting the progression of endometriosis

This observation in the model predictions indicates that our model supports the hinge-latch hypothesis 36