Moreover, NASH patients demonstrated impaired synthesis and excretion of lipoproteins [13, 38], indicating that there is a limited capability of excretion of VLDL particles, which might be secondary to hepatocellular impairment [38, 39]
And that sense of hope is completely understandable
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1,000 to 1,200 mg daily, based on body weight less than or greater than 75 kg (it has been recently suggested that the heaviest patients could even benefit from a higher ribavirin dose, up to 1,600 mg daily) and they theoretically require 48 weeks of treatment (Figure 1A) [18 ]