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293 NQO1, an enzyme involved in the elimination of ROS, is inhibited by HBx, leading to decreased GSH levels and increased susceptibility of hepatoma cells to oxidative damage, cumulating in HBV-associated pathogenesis of chronic liver diseases

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Yoshida H, Arai S, Hara KY, Yamada R, Ogino C, Fukuda H, Kondo A (2011) Efficient and direct glutathione production from raw starch using engineered Saccharomyces cerevisiae

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