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If you are taking other medications for your blood pressure these may have to be reviewed as you may need to reduce the doses to avoid going too low

If any of these apply, the semaglutide to tirzepatide switching guide covers the reverse transition

The Journal of clinical endocrinology and metabolism, 96(4), E614E623

Interactions with other substances Retatrutide affects gastric emptying, which means it can alter the absorption kinetics of other substances taken orally

These drugs are peptide molecules, meaning they are built from chains of amino acids

Gastrointestinal adverse events of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a systematic review and network meta-analysis