side effects of the glp 1 patch How to Wear GLP-1 Patches: Current Status and Approved Alternatives Why GLP-1 Patches Don't Deliver—Yet

The gastrointestinal side effects of GLP-1 agentsparticularly vomiting and diarrheacan lead to depletion of essential electrolytes including sodium, magnesium, potassium, and calcium, all of which are critical for normal muscle contraction and relaxation

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GLP-1 s also inhibit gastric emptying and induce gastroparesis, which induces satiety and reduces appetite and food intake, therefore limiting weight gain [1]

Other complementary compounds, such as carnitines (12), L-arginine (L-ARG) and N-acetyl-cysteine (NAC) (13), have also been reported to counteract compensatory hyperinsulinemia

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Therefore, one of the reasons for not achieving a significant result in the present study could be related to the low dose of L-carnitine intervention (1000 mg/day)