Use Berberine for Supportive Effects Berberine is getting a lot of media attention for its potential ability to promote GLP-1 activity and more in ways that may be useful in supporting those on GLP-1 agonists .[21-23] Berberine is an alkaloid compound found in many plants, most notably goldenseal (Hydrastis canadensis), barberry (Berberis vulgaris), and goldthread (Coptis chinensis)
The core of my own philosophy on drug therapeutics is that we should strive to produce treatments with zero side effects, says De Jonghe
Physiological Reviews 86 (1): 205-43
The methylcobalamin component at 5mg/mL is a substantial B12 dose
Non-inferiority (NI) of treatment with SEM versus active comparators (SUSTAIN-2, 3, 4, and 7) on glycemic control was assessed in four SUSTAIN trials
So the reason you're seeing the clamoring is that you have these groups fighting for the limited supply of these expensive drugs