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It adds that health professionals have a key role in identifying and managing the risks associated with unregistered GLP-1 products and should advise patients accordingly

Critical safety thresholds have been established for compounds like EGCG (800 mg/day limit) (240) and -carotene (contraindicated in smokers), while hepatotoxicity cases linked to curcumin formulations have prompted regulatory warnings across multiple jurisdictions

154 To be included in the trial participants had to test positive, above a predetermined threshold, for at least four of the nine metals in a urinary test panel (ie, aluminum, antimony, arsenic, bismuth, cadmium, lead, mercury, nickel, and tin)

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