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For instance, in an 8-week randomized controlled trial, tirzepatide treatment significantly reduced LDL cholesterol and C-reactive protein levels in patients with type 2 diabetes ( Given that tirzepatide activates both GLP-1 and GIP signaling pathways, its cardiovascular benefits may arise not only from the effects of GLP-1 but also from the potential effects of GIP

doi: 10.1007/s00592-017-1031-9

GLP-1 agonists are contraindicated in patients with personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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Try anti-nausea medications If youre experiencing nausea from semaglutide, prescription anti-nausea medications like Zofran (ondansetron) may help