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GSH acts as a cofactor for antioxidant enzymes such as GPX4, which play a role in the elimination of ROS

In all the other key areas, mitochondrial function, mitophagy, nutrient sensing, and genomic stability, the results were equally impressive: the markers bounced back almost to the levels observed in young mice.

Compounds containing sulfur are usually good antioxidants able to accommodate unpaired electron(s), which in turn result in the formation of thiyl radicals (GS ), whose lifetime is rather high and therefore damage to biological molecules is very mild (Karoui et al

Biomarkers: Multiple blood and CSF biomarkers were collected (see figure below) - the CSF biomarkers were only in a subset of patients (199) who agreed to participate in a substudy

individual results are unique and will vary

Digestive and Liver Disease, 35 (9), 635641