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PMID 22450609

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In 1998, IM-TOFMS analysis of bradykinin and ubiquitin ions formed by ESI revealed that it is possible to simultaneously record mass-resolved mobilities for all ions present in ESI distributions, thereby providing a means for direct measurement of conformer- and mass-to-charge ( m/z )-resolved abundances for the total distribution of ions and generating 3D spectra that contain collision cross section, mass-to-charge, and ion abundance information (Hoaglund et al., 1998)

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These effects are well-documented in rodents without observed toxic or lethal thresholds

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