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GLP-1 side effects tend to be worst during the first few weeks of treatment or after dose increases, then gradually improve as the body adjusts

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A randomized, double-blind, placebo-controlled study of 60 overweight women with polycystic ovary syndrome (PCOS) showed that 250 mg/day L-Carnitine for 12 weeks significantly reduced body weight (average 2.7 kg loss), BMI, waist, and hip circumference compared to placebo [14]

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