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In regard to eNOS function, 5-methyltetrahydrofolate (MTHF), the active form of folic acid, does not have an effect on pterin-free eNOS, but directly interferes with BH 4 -repleted, partially uncoupled eNOS, shifting it from superoxide production toward NO production (Stroes et al., 2000)

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The metabolic hormone leptin promotes the function of T(Fh) cells and supports vaccine responses

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PLoS One 2012;7:e49152

Analyses of Pet1 knockout mice, in which most dorsal raphe neurons lacked 5-HT, revealed that 5-HT in the fetal forebrain was of placental and not maternal or fetal origin (131)