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GLP-1 medications are engineered to mimic glucagon-like peptide-1, he explains, a hormone the gut naturally releases after a meal. However, while the version produced by the body peaks and clears within minutes, the medication version keeps that signal active for days, he adds

By week 2, many users report strong food aversion becoming common-a significant shift in how the body responds to hunger cues

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Small molecules are chemically synthesized and designed to interact with receptors and enzymes, says Dr

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When a small group of patients began taking a very tiny dose starting at 0.0675 mg, compared to the label-recommended 0.25 mg and increased it gradually, they were able to tolerate it better than the folks who started the usual dose and tried to escalate it in the typical way, says Alkhaddo