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GLP-1 agonists are not new to the pharmaceutical landscape

This is one of the primary arguments for the microdosing approach in autoimmune patients

There are also new formulations that act on other receptors in addition to GLP-1 receptors to significantly increase the medication's effectiveness , in some cases doubling the weight reduction patients experience

Effect of exenatide on gastric emptying and relationship to postprandial glycemia in type 2 diabetes

Youre going from a dual-receptor medication to a single-receptor one, and for many patients, that difference is noticeable