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Cell Mol Life Sci 60:350377

2021 study published in Pharmaceutics used physiologically-based pharmacokinetic (PBPK) modeling in pregnant women and found: Just before giving birth, the clearance level (CL) of acetaminophen via the toxic pathway was 1.8-fold higher than shortly after delivery

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To prevent these free radicals from destroying healthy tissue and organs, the body rapidly deploys its endogenous antioxidant enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx)