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[fonte] Referncias: Armenian SH et al

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A specific probe-substrate (cocktail assay) coupled with fast liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis was developed in human liver microsomes (Zhou et al., 2022)

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The proportion of patients who discontinued for lack of glycemic control or who were rescued for meeting prespecified glycemic criteria was 15% in the saxagliptin 2.5 mg add-on to metformin HCl immediate-release group, 13% in the saxagliptin 5 mg add-on to metformin HCl immediate-release group, and 27% in the placebo add-on to metformin HCl immediate-release group