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Additionally, GIP-mediated cAMP elevation activates exchange protein directly activated by cAMP 2 (Epac2), which stimulates ryanodine receptors (RYRs) on the endoplasmic reticulum to release stored calcium, further increasing cytosolic Ca concentration

The pharmacokinetic profile of liraglutide injection in the pediatric patients was consistent with that in adults

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This distinction affects storage requirements