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Cold weather also leads to cold-induced diuresis, meaning your body loses more fluid even if you dont feel thirsty (2)

The answer depends on the person, some people benefit from a weekly injection, while others may only need one every two to four weeks

Source: meta-analyses across SURPASS

-Immunomodulation and inflammatory response

[20] [21] Patients experiencing persistent vomiting or diarrhoea should contact their healthcare provider promptly, as severe gastrointestinal symptoms can increase the risk of acute kidney injury, particularly in vulnerable individuals