36-38 In patients with a GH-receptor deficiency (primary IGF-I deficiency, Laron syndrome), bone mass has long been suggested to be low, but this tenet might not be true because there is increasing evidence that when volumetric bone mineral density is measured there are no changes in bone mass, probably due to the small bone area and short stature of these patients
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It does not add gluteal volume unless the surgeon includes fat transfer
Developed by Theratechnologies (Montreal), Tesamorelin is a 44-amino-acid analog of native GHRH, stabilized by a trans-3-hexenoic group attached at the N-terminal position