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One of these side effects is weight gain

They found that microbial infections, such as SARS and H5N1 virus infections in the lungs, trigger NADPH-dependent ROS production, thereby generating oxidized phospholipids, such as oxidized 1-palmitoyl-2-arachidonoyl-sn-glycerol-3-phosphatidylcholine, to induce lung injury and cytokine production by lung macrophages via TLR4TRIF 80

Specifically, sCT caused weight gain in WT mice while inducing initial weight loss followed by partial weight regain in HFD-fed RAMP1/3 KO mice

Ethics declarations Competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper

Consequently, targeting oxidative stress emerges as a promising therapeutic approach for OA

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