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68 , acute tubulointerstitial nephrotoxicity brought on by xenobiotics, such as cisplatin-induced nephrotoxicity due to oxidative stress, is associated with an increase in urinary KIM-1
neural progenitor cells generate molecular signals driving the migration of the endothelial cells, which in turn secrete cues to recruit pericytes
& Pridal, L
Eventually, GABA is removed from the system by converting it into succinate, which is then used in the Krebs cycle in the mitochondria to make ATP.[ref] The enzyme succinic semialdehyde dehydrogenase ( ALDH5A1 gene) is needed to convert GABA into succinate.[ref] Rare genetic mutations in the ALDH5A1 gene cause succinic semialdehyde dehydrogenase deficiency, which decreases the breakdown of GABA